Impaired Wheel Running Exercise in CLC-1 Chloride Channel-Deficient Myotonic Mice
نویسندگان
چکیده
منابع مشابه
Impaired Wheel Running Exercise in CLC-1 Chloride Channel-Deficient Myotonic Mice
BACKGROUND Genetic deficiency of the muscle CLC-1 chloride channel leads to myotonia, which is manifested most prominently by slowing of muscle relaxation. Humans experience this as muscle stiffness upon initiation of contraction, although this can be overcome with repeated efforts (the "warm-up" phenomenon). The extent to which CLC-1 deficiency impairs exercise activity is controversial. We hy...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2011
ISSN: 1664-042X
DOI: 10.3389/fphys.2011.00047